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Design Protein Binder Candidates with Boltz

Submit a target and design constraints to Boltz to generate protein, peptide, or antibody binder candidates and monitor the job.

Skills

Use only when the user wants new protein, peptide, antibody, or nanobody binders; it is not for screening existing proteins or small molecules. Check target sequence, chain, and user constraints, choose the Boltz design command/options, then record the job ID and retrieve results through the status workflow. Generated structures are computational candidates, not experimentally validated or ready for therapeutic use.

Permissions

Prerequisites

Permissions

Limitations

Results depend on model and compute conditions and need expert structural and experimental evaluation; the skill cannot prove binding.

Pinned upstream source

https://github.com/openai/plugins/blob/0722921d5542fc593105c27bd52630babd8b8c2a/plugins/boltz-api-cli/skills/boltz-protein-design/SKILL.md

Repository
openai/plugins
File path
plugins/boltz-api-cli/skills/boltz-protein-design/SKILL.md
Pinned commit
0722921d5542fc593105c27bd52630babd8b8c2a
Source checked
2026-10-14 · Reviewed against the pinned upstream source

Repository metrics

These values describe the upstream repository, not popularity or likes for an individual skill or playbook.

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License: MIT

Compatible tools

Codex · Boltz API CLI

View skill directory

Main topic

Turn ecommerce campaign materials into a reviewable weekly brief

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